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| 29.01.1999 | 20:00 | Club Brugge KV | - | RSC Anderlecht | 2:0 (0:0) | |
| 30.01.1999 | 20:00 | Sint-Truidense VV | - | K.S.C. Eendracht Aalst | 2:0 (1:0) | |
| 20:00 | KSK Beveren | - | Lierse SK | 1:3 (0:2) | ||
| 20:00 | Excelsior Mouscron | - | Sporting Lokeren | 5:1 (1:1) | ||
| 20:00 | KVC Westerlo | - | KRC Harelbeke | 0:3 (0:0) | ||
| 20:00 | KRC Genk | - | KAA Gent | 1:0 (0:0) | ||
| 20:00 | RSC Charleroi | - | KV Oostende | 1:1 (1:0) | ||
| 31.01.1999 | 15:00 | Germinal Beerschot | - | Lommelse SK | 1:0 (1:0) | |
| 15:00 | KV Kortrijk | - | Standard Liège | 1:3 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk | 22 | 14 | 5 | 3 | 49:25 | 24 | 47 |
| 2 |
|
Club Brugge KV | 22 | 14 | 4 | 4 | 40:22 | 18 | 46 |
| 3 |
|
Excelsior Mouscron | 22 | 11 | 7 | 4 | 50:34 | 16 | 40 |
| 4 |
|
RSC Anderlecht | 22 | 11 | 5 | 6 | 41:32 | 9 | 38 |
| 5 |
|
Sporting Lokeren | 22 | 11 | 4 | 7 | 46:35 | 11 | 37 |
| 6 |
|
KAA Gent | 22 | 10 | 7 | 5 | 37:37 | 0 | 37 |
| 7 |
|
Sint-Truidense VV | 22 | 10 | 6 | 6 | 31:24 | 7 | 36 |
| 8 |
|
Standard Liège | 22 | 11 | 2 | 9 | 35:27 | 8 | 35 |
| 9 |
|
Germinal Beerschot | 22 | 10 | 4 | 8 | 36:32 | 4 | 34 |
| 10 |
|
Lierse SK | 22 | 10 | 3 | 9 | 42:35 | 7 | 33 |
| 11 |
|
KVC Westerlo | 22 | 9 | 3 | 10 | 43:40 | 3 | 30 |
| 12 |
|
KRC Harelbeke | 22 | 6 | 8 | 8 | 29:34 | -5 | 26 |
| 13 |
|
K.S.C. Eendracht Aalst | 22 | 7 | 5 | 10 | 30:39 | -9 | 26 |
| 14 |
|
RSC Charleroi | 22 | 4 | 9 | 9 | 27:34 | -7 | 21 |
| 15 |
|
Lommelse SK | 22 | 5 | 4 | 13 | 23:35 | -12 | 19 |
| 16 |
|
KSK Beveren | 22 | 4 | 4 | 14 | 23:40 | -17 | 16 |
| 17 |
|
KV Kortrijk | 22 | 3 | 5 | 14 | 31:56 | -25 | 14 |
| 18 |
|
KV Oostende | 22 | 2 | 7 | 13 | 20:52 | -32 | 13 |
