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| 22.09.2010 | 14:30 | Naftan Novopolotsk | - | FK Gorodeya | 4:2 | |
| 15:00 | Belshina Bobruisk | - | Kommunalnik Slonim | 2:1 n.V. | ||
| 15:00 | FK Minsk | - | DSK Gomel | 3:1 n.V. | ||
| 15:00 | FK Rudensk | - | FK Gomel | 0:5 | ||
| 16:00 | FK Vitebsk | - | Neman Grodno | 4:5 i.E. | ||
| 18:00 | Shakhter Soligorsk | - | Volna Pinsk | 4:0 n.V. | ||
| 27.10.2010 | 14:00 | Partizan Minsk | - | Dinamo Minsk | 1:0 (0:0) | |
| 27.11.2010 | 15:00 | BATE Borisov | - | Dinamo Brest | 0:1 (0:1) |
