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| 11.12.2016 | 12:00 | Real Murcia | - | La Roda CF | 0:1 (0:0) | |
| 12:00 | UD Melilla | - | Córdoba CF B | 2:1 (1:0) | ||
| 12:00 | Granada CF B | - | Linares Deportivo | 3:0 (2:0) | ||
| 16:00 | Real Jaén | - | CF Villanovense | 1:1 (0:1) | ||
| 17:00 | Mérida AD | - | CD El Ejido 2012 | 2:0 (1:0) | ||
| 17:00 | Lorca FC | - | Atlético Mancha Real | 3:0 (2:0) | ||
| 17:00 | San Fernando CD | - | Recreativo Huelva | 2:2 (0:1) | ||
| 17:00 | Marbella FC | - | FC Jumilla | 0:0 (0:0) | ||
| 17:00 | Atlético Sanluqueño CF | - | Extremadura UD | 3:0 (1:0) | ||
| 17:30 | FC Cartagena | - | RB Linense | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 18 | 11 | 4 | 3 | 28:13 | 15 | 37 |
| 2 |
|
Marbella FC | 18 | 10 | 3 | 5 | 26:22 | 4 | 33 |
| 3 |
|
CF Villanovense | 18 | 9 | 5 | 4 | 30:18 | 12 | 32 |
| 4 |
|
Lorca FC | 18 | 9 | 5 | 4 | 26:22 | 4 | 32 |
| 5 |
|
Mérida AD | 18 | 9 | 2 | 7 | 25:21 | 4 | 29 |
| 6 |
|
FC Jumilla | 18 | 8 | 5 | 5 | 15:11 | 4 | 29 |
| 7 |
|
UD Melilla | 18 | 7 | 7 | 4 | 21:14 | 7 | 28 |
| 8 |
|
Real Murcia | 18 | 8 | 3 | 7 | 16:17 | -1 | 27 |
| 9 |
|
San Fernando CD | 18 | 8 | 3 | 7 | 23:22 | 1 | 27 |
| 10 |
|
Linares Deportivo | 18 | 7 | 4 | 7 | 20:19 | 1 | 25 |
| 11 |
|
Granada CF B | 18 | 6 | 5 | 7 | 26:21 | 5 | 23 |
| 12 |
|
Atlético Mancha Real | 18 | 7 | 2 | 9 | 29:34 | -5 | 23 |
| 13 |
|
Real Jaén | 18 | 4 | 10 | 4 | 22:19 | 3 | 22 |
| 14 |
|
CD El Ejido 2012 | 18 | 6 | 4 | 8 | 23:25 | -2 | 22 |
| 15 |
|
RB Linense | 18 | 5 | 6 | 7 | 22:29 | -7 | 21 |
| 16 |
|
Córdoba CF B | 18 | 5 | 6 | 7 | 19:19 | 0 | 21 |
| 17 |
|
Recreativo Huelva | 18 | 3 | 9 | 6 | 13:20 | -7 | 18 |
| 18 |
|
La Roda CF | 18 | 3 | 7 | 8 | 21:26 | -5 | 16 |
| 19 |
|
Extremadura UD | 18 | 3 | 5 | 10 | 14:32 | -18 | 14 |
| 20 |
|
Atlético Sanluqueño CF | 18 | 2 | 5 | 11 | 15:30 | -15 | 11 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
