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| 21.01.2006 | 18:30 | Levante UD | - | UE Lleida | 2:0 (0:0) | |
| 18:30 | Real Murcia | - | Sporting Gijón | 1:0 (1:0) | ||
| 18:30 | Albacete | - | CD Tenerife | 3:2 (2:1) | ||
| 18:30 | Atlético Malagueño | - | Xerez CD | 0:0 (0:0) | ||
| 22.01.2006 | 12:00 | Elche CF | - | Real Valladolid | 0:2 (0:2) | |
| 17:00 | Polideportivo Ejido | - | Lorca Deportiva | 2:3 (0:2) | ||
| 17:00 | Racing Ferrol | - | SD Eibar | 4:0 (1:0) | ||
| 17:00 | Gimnàstic de Tarragona | - | Ciudad de Murcia | 2:0 (0:0) | ||
| 17:00 | Recreativo Huelva | - | Hércules CF | 1:0 (1:0) | ||
| 17:30 | Real Madrid Castilla | - | CD Numancia | 1:1 (1:1) | ||
| 18:00 | UD Almería | - | CD Castellón | 2:1 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Xerez CD | 21 | 12 | 7 | 2 | 35:18 | 17 | 43 |
| 2 |
|
Recreativo Huelva | 21 | 11 | 7 | 3 | 33:19 | 14 | 40 |
| 3 |
|
Real Valladolid | 21 | 8 | 10 | 3 | 30:22 | 8 | 34 |
| 4 |
|
Levante UD | 21 | 9 | 7 | 5 | 30:23 | 7 | 34 |
| 5 |
|
UD Almería | 21 | 10 | 4 | 7 | 28:21 | 7 | 34 |
| 6 |
|
Gimnàstic de Tarragona | 21 | 10 | 2 | 9 | 21:23 | -2 | 32 |
| 7 |
|
Lorca Deportiva | 21 | 8 | 7 | 6 | 27:20 | 7 | 31 |
| 8 |
|
Sporting Gijón | 21 | 7 | 9 | 5 | 25:19 | 6 | 30 |
| 9 |
|
Real Murcia | 21 | 8 | 6 | 7 | 21:19 | 2 | 30 |
| 10 |
|
Elche CF | 21 | 8 | 6 | 7 | 28:31 | -3 | 30 |
| 11 |
|
Ciudad de Murcia | 21 | 7 | 7 | 7 | 23:28 | -5 | 28 |
| 12 |
|
Albacete | 21 | 7 | 6 | 8 | 22:28 | -6 | 27 |
| 13 |
|
Real Madrid Castilla | 21 | 7 | 5 | 9 | 28:24 | 4 | 26 |
| 14 |
|
Hércules CF | 21 | 6 | 8 | 7 | 24:27 | -3 | 26 |
| 15 |
|
Racing Ferrol | 21 | 5 | 10 | 6 | 27:28 | -1 | 25 |
| 16 |
|
CD Tenerife | 21 | 6 | 5 | 10 | 27:35 | -8 | 23 |
| 17 |
|
CD Numancia | 21 | 5 | 8 | 8 | 18:29 | -11 | 23 |
| 18 |
|
UE Lleida | 21 | 6 | 4 | 11 | 20:25 | -5 | 22 |
| 19 |
|
CD Castellón | 21 | 5 | 7 | 9 | 19:25 | -6 | 22 |
| 20 |
|
Polideportivo Ejido | 21 | 6 | 4 | 11 | 24:31 | -7 | 22 |
| 21 |
|
SD Eibar | 21 | 4 | 9 | 8 | 16:24 | -8 | 21 |
| 22 |
|
Atlético Malagueño | 21 | 4 | 6 | 11 | 15:22 | -7 | 18 |
