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| 14.01.2011 | 21:00 | Girona FC | - | CD Numancia | 2:0 (1:0) | |
| 15.01.2011 | 16:00 | Real Betis | - | AD Alcorcón | 3:0 (1:0) | |
| 18:00 | Real Valladolid | - | SD Huesca | 2:0 (1:0) | ||
| 18:00 | Albacete | - | Gimnàstic de Tarragona | 0:1 (0:0) | ||
| 18:00 | UD Las Palmas | - | Córdoba CF | 0:1 (0:1) | ||
| 18:00 | UD Salamanca | - | FC Barcelona B | 2:3 (1:1) | ||
| 18:00 | Rayo Vallecano | - | FC Cartagena | 3:1 (2:1) | ||
| 18:00 | RC Celta | - | Xerez CD | 1:1 (1:0) | ||
| 16.01.2011 | 12:00 | Elche CF | - | Granada CF | 0:0 (0:0) | |
| 17:00 | Recreativo Huelva | - | Villarreal CF B | 2:0 (1:0) | ||
| 17:00 | SD Ponferradina | - | CD Tenerife | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Betis | 20 | 14 | 4 | 2 | 46:17 | 29 | 46 |
| 2 |
|
RC Celta | 20 | 11 | 7 | 2 | 36:19 | 17 | 40 |
| 3 |
|
Rayo Vallecano | 20 | 12 | 4 | 4 | 33:20 | 13 | 40 |
| 4 |
|
FC Cartagena | 20 | 9 | 5 | 6 | 30:25 | 5 | 32 |
| 5 |
|
Xerez CD | 20 | 9 | 4 | 7 | 31:28 | 3 | 31 |
| 6 |
|
FC Barcelona B | 20 | 8 | 7 | 5 | 32:30 | 2 | 31 |
| 7 |
|
Granada CF | 20 | 7 | 7 | 6 | 34:24 | 10 | 28 |
| 8 |
|
Villarreal CF B | 20 | 8 | 4 | 8 | 24:31 | -7 | 28 |
| 9 |
|
CD Numancia | 20 | 8 | 3 | 9 | 29:24 | 5 | 27 |
| 10 |
|
Elche CF | 20 | 6 | 9 | 5 | 18:19 | -1 | 27 |
| 11 |
|
Real Valladolid | 20 | 7 | 5 | 8 | 28:27 | 1 | 26 |
| 12 |
|
Girona FC | 20 | 6 | 7 | 7 | 27:26 | 1 | 25 |
| 13 |
|
Córdoba CF | 20 | 5 | 9 | 6 | 26:27 | -1 | 24 |
| 14 |
|
UD Salamanca | 20 | 7 | 3 | 10 | 23:27 | -4 | 24 |
| 15 |
|
Albacete | 20 | 5 | 8 | 7 | 17:20 | -3 | 23 |
| 16 |
|
Recreativo Huelva | 20 | 4 | 10 | 6 | 19:21 | -2 | 22 |
| 17 |
|
SD Huesca | 20 | 4 | 10 | 6 | 14:20 | -6 | 22 |
| 18 |
|
UD Las Palmas | 20 | 5 | 7 | 8 | 29:39 | -10 | 22 |
| 19 |
|
AD Alcorcón | 20 | 6 | 3 | 11 | 22:31 | -9 | 21 |
| 20 |
|
Gimnàstic de Tarragona | 20 | 4 | 7 | 9 | 15:23 | -8 | 19 |
| 21 |
|
SD Ponferradina | 20 | 3 | 8 | 9 | 17:37 | -20 | 17 |
| 22 |
|
CD Tenerife | 20 | 3 | 7 | 10 | 17:32 | -15 | 16 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
