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| 08.04.2022 | 20:00 | FC Rouen 1899 | - | FC Versailles | 1:1 (1:1) | |
| 09.04.2022 | 18:00 | AS Poissy | - | EA Guingamp (CFA) | 1:1 (1:0) | |
| 18:00 | AS Vitré | - | SM Caen (CFA) | 2:0 (1:0) | ||
| 18:00 | C'Chartres Football | - | FC Lorient (CFA) | 2:5 (0:2) | ||
| 18:00 | US Granvillaise | - | Stade Plabennec | 2:2 (1:2) | ||
| 18:00 | SO Romorantin | - | US Saint-Malo | 2:1 (1:1) | ||
| 18:00 | Châteaubriant Voltigeurs | - | Blois Foot 41 | 1:0 (1:0) | ||
| 18:30 | Vannes OC | - | St-Pryvé St-Hilaire | 3:3 (2:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Versailles | 24 | 13 | 10 | 1 | 35:13 | 22 | 49 |
| 2 |
|
FC Lorient (CFA) | 24 | 14 | 5 | 5 | 39:19 | 20 | 47 |
| 3 |
|
C'Chartres Football | 24 | 13 | 3 | 8 | 43:34 | 9 | 42 |
| 4 |
|
Vannes OC | 24 | 10 | 7 | 7 | 37:30 | 7 | 37 |
| 5 |
|
St-Pryvé St-Hilaire | 24 | 10 | 6 | 8 | 32:28 | 4 | 36 |
| 6 |
|
Blois Foot 41 | 24 | 10 | 6 | 8 | 37:40 | -3 | 36 |
| 7 |
|
Châteaubriant Voltigeurs | 24 | 9 | 5 | 10 | 26:28 | -2 | 32 |
| 8 |
|
FC Rouen 1899 | 24 | 7 | 10 | 7 | 25:24 | 1 | 31 |
| 9 |
|
SM Caen (CFA) | 24 | 8 | 6 | 10 | 24:32 | -8 | 30 |
| 10 |
|
AS Poissy | 24 | 6 | 11 | 7 | 27:31 | -4 | 29 |
| 11 |
|
EA Guingamp (CFA) | 24 | 7 | 8 | 9 | 29:37 | -8 | 29 |
| 12 |
|
US Saint-Malo | 24 | 7 | 5 | 12 | 21:30 | -9 | 26 |
| 13 |
|
US Granvillaise | 24 | 4 | 13 | 7 | 22:25 | -3 | 25 |
| 14 |
|
SO Romorantin | 24 | 6 | 6 | 12 | 21:34 | -13 | 24 |
| 15 |
|
AS Vitré | 24 | 5 | 8 | 11 | 27:33 | -6 | 23 |
| 16 |
|
Stade Plabennec | 24 | 5 | 7 | 12 | 23:30 | -7 | 22 |
| Aufstieg | |
| Abstieg |
