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| 04.02.2022 | 19:30 | Bergerac Foot | - | FC Chamalières | 1:0 (1:0) | |
| 05.02.2022 | Le Puy Foot 43 | - | Canet Roussillon | 3:0 Wert. | ||
| 18:00 | AS Béziers | - | Moulins Yzeure Foot | 3:2 (0:2) | ||
| 18:00 | Montpellier HSC (CFA) | - | Andrézieux-Bouthéon FC | 0:2 (0:2) | ||
| 18:00 | Angers SCO II | - | FC Nantes (CFA) | 1:0 (0:0) | ||
| 18:00 | Vendée Les Herbiers | - | US Colomiers | 1:3 (0:2) | ||
| 18:30 | Stade Montois | - | Trélissac FC | 0:3 (0:2) | ||
| 26.02.2022 | 18:00 | Bourges Foot 18 | - | Angoulême CFC | 0:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bergerac Foot | 17 | 10 | 5 | 2 | 22:9 | 13 | 35 |
| 2 |
|
Angoulême CFC | 17 | 9 | 5 | 3 | 25:15 | 10 | 32 |
| 3 |
|
Le Puy Foot 43 | 17 | 8 | 5 | 4 | 22:11 | 11 | 29 |
| 4 |
|
Andrézieux-Bouthéon FC | 17 | 9 | 2 | 6 | 23:16 | 7 | 29 |
| 5 |
|
AS Béziers | 17 | 8 | 4 | 5 | 23:17 | 6 | 28 |
| 6 |
|
Moulins Yzeure Foot | 17 | 7 | 7 | 3 | 17:13 | 4 | 28 |
| 7 |
|
Bourges Foot 18 | 17 | 8 | 3 | 6 | 24:15 | 9 | 27 |
| 8 |
|
FC Nantes (CFA) | 17 | 6 | 7 | 4 | 22:16 | 6 | 25 |
| 9 |
|
Trélissac FC | 17 | 6 | 4 | 7 | 14:14 | 0 | 22 |
| 10 |
|
Angers SCO II | 17 | 5 | 6 | 6 | 19:18 | 1 | 21 |
| 11 |
|
Vendée Les Herbiers | 17 | 5 | 6 | 6 | 20:24 | -4 | 21 |
| 12 |
|
FC Chamalières | 17 | 5 | 3 | 9 | 21:27 | -6 | 18 |
| 13 |
|
US Colomiers | 17 | 4 | 6 | 7 | 15:21 | -6 | 18 |
| 14 |
|
Canet Roussillon | 17 | 7 | 4 | 6 | 15:22 | -7 | 14 |
| 15 |
|
Montpellier HSC (CFA) | 17 | 4 | 2 | 11 | 17:28 | -11 | 14 |
| 16 |
|
Stade Montois | 17 | 0 | 1 | 16 | 12:45 | -33 | 1 |
| Aufstieg | |
| Abstieg |
