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| H | AO Kerkyra | - | Olympiakos Volou | 0:2 (0:1) | ||
| R | Olympiakos Volou | - | AO Kerkyra | 1:2 (1:1) | ||
| H: 18.01.2011 16:00 | R: 03.02.2011 18:00 | Sieger: Olympiakos Volou | ||||
| H | Olympiakos Piraeus | - | PAOK Saloniki | 1:1 (1:0) | ||
| R | PAOK Saloniki | - | Olympiakos Piraeus | 1:0 (0:0) | ||
| H: 19.01.2011 17:00 | R: 02.02.2011 17:00 | Sieger: PAOK Saloniki | ||||
| H | Panathinaikos | - | AEK Athen | 0:2 (0:0) | ||
| R | AEK Athen | - | Panathinaikos | 2:3 (1:2) | ||
| H: 19.01.2011 20:00 | R: 02.02.2011 20:00 | Sieger: AEK Athen | ||||
| H | Atromitos | - | Diagoras FC | 2:0 (1:0) | ||
| R | Diagoras FC | - | Atromitos | 0:1 (0:1) | ||
| H: 20.01.2011 18:00 | R: 03.02.2011 15:00 | Sieger: Atromitos | ||||
