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| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSC Bari | 18 | 10 | 6 | 2 | 21:11 | 10 | 36 |
| 2 |
|
US Avellino | 17 | 8 | 5 | 4 | 17:10 | 7 | 29 |
| 3 |
|
US Catanzaro | 17 | 7 | 6 | 4 | 22:14 | 8 | 27 |
| 4 |
|
Monterosi FC | 18 | 5 | 7 | 6 | 18:22 | -4 | 22 |
| 5 |
|
SS Monopoli 1966 | 18 | 6 | 4 | 8 | 15:21 | -6 | 22 |
| 6 |
|
FC Turris | 18 | 6 | 4 | 8 | 22:29 | -7 | 22 |
| 7 |
|
Campobasso | 18 | 6 | 4 | 8 | 26:37 | -11 | 22 |
| 8 |
|
AZ Picerno | 18 | 5 | 5 | 8 | 17:29 | -12 | 20 |
| 9 |
|
Foggia Calcio | 18 | 3 | 10 | 5 | 22:25 | -3 | 19 |
| 10 |
|
Palermo FC | 17 | 4 | 7 | 6 | 20:24 | -4 | 19 |
| 11 |
|
Virtus Francavilla | 17 | 4 | 4 | 9 | 10:16 | -6 | 16 |
| 12 |
|
SS Juve Stabia | 18 | 3 | 6 | 9 | 13:25 | -12 | 15 |
| 13 |
|
Fidelis Andria | 17 | 3 | 5 | 9 | 12:22 | -10 | 14 |
| 14 |
|
ACR Messina | 18 | 3 | 5 | 10 | 20:37 | -17 | 14 |
| 15 |
|
Latina Calcio | 17 | 3 | 3 | 11 | 14:27 | -13 | 12 |
| 16 |
|
Potenza | 17 | 3 | 3 | 11 | 14:31 | -17 | 12 |
| 17 |
|
Taranto FC | 17 | 2 | 4 | 11 | 13:30 | -17 | 10 |
| 18 |
|
Paganese Calcio | 17 | 0 | 5 | 12 | 10:34 | -24 | 5 |
| 19 |
|
Vibonese Calcio | 18 | 0 | 5 | 13 | 11:37 | -26 | 5 |
| 20 |
|
Calcio Catania | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
|
# Calcio Catania ging im Frühjahr 2022 bankrott und wurde vom professionellen Fußball ausgeschlossen. Alle Saisonspiele des Vereins wurden annulliert. |
