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| 30.05.2021 | 14:30 | ASG Nocerina | - | Muravera | 1:1 | |
| 14:30 | Lanusei Calcio | - | AC Savoia 1908 | 1:1 | ||
| 15:00 | ASD Carbonia Calcio | - | Afragolese | 2:2 | ||
| 15:00 | SEF Torres 1903 | - | Cassino Calcio 1924 | 2:1 | ||
| 15:00 | ASD SS Nola 1925 | - | Sassari Latte Dolce | 3:5 | ||
| 16:00 | Formia | - | Arzachena | 4:2 | ||
| 16:00 | Monterosi FC | - | Latina Calcio | 2:0 | ||
| 16:00 | Team Nuova Florida | - | Giugliano | 3:0 | ||
| 16:00 | ASD Vis Artena | - | Gladiator | 1:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Monterosi FC | 31 | 22 | 8 | 1 | 53:19 | 34 | 74 |
| 2 |
|
Latina Calcio | 31 | 17 | 8 | 6 | 54:22 | 32 | 59 |
| 3 |
|
ASD Vis Artena | 31 | 16 | 4 | 11 | 50:38 | 12 | 52 |
| 4 |
|
AC Savoia 1908 | 31 | 12 | 14 | 5 | 35:20 | 15 | 50 |
| 5 |
|
ASG Nocerina | 31 | 12 | 13 | 6 | 47:31 | 16 | 49 |
| 6 |
|
Muravera | 31 | 13 | 7 | 11 | 41:37 | 4 | 46 |
| 7 |
|
Formia | 31 | 11 | 11 | 9 | 46:34 | 12 | 44 |
| 8 |
|
ASD Carbonia Calcio | 31 | 11 | 9 | 11 | 50:49 | 1 | 42 |
| 9 |
|
Lanusei Calcio | 31 | 10 | 11 | 10 | 39:34 | 5 | 41 |
| 10 |
|
Cassino Calcio 1924 | 31 | 9 | 13 | 9 | 37:40 | -3 | 40 |
| 11 |
|
Sassari Latte Dolce | 31 | 10 | 9 | 12 | 37:35 | 2 | 39 |
| 12 |
|
Team Nuova Florida | 31 | 8 | 13 | 10 | 34:42 | -8 | 37 |
| 13 |
|
Arzachena | 31 | 7 | 14 | 10 | 38:45 | -7 | 35 |
| 14 |
|
Gladiator | 31 | 7 | 12 | 12 | 31:43 | -12 | 33 |
| 15 |
|
SEF Torres 1903 | 31 | 7 | 9 | 15 | 27:44 | -17 | 30 |
| 16 |
|
Afragolese | 31 | 7 | 7 | 17 | 35:57 | -22 | 28 |
| 17 |
|
ASD SS Nola 1925 | 31 | 5 | 13 | 13 | 30:53 | -23 | 27 |
| 18 |
|
Giugliano | 31 | 5 | 5 | 21 | 22:63 | -41 | 20 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
