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| 09.06.2021 | 15:00 | ASD Carbonia Calcio | - | ASD Vis Artena | 2:0 | |
| 16:00 | Arzachena | - | Muravera | 0:0 | ||
| 16:00 | ASG Nocerina | - | Latina Calcio | 4:0 | ||
| 16:00 | Giugliano | - | Monterosi FC | 3:6 | ||
| 16:00 | Gladiator | - | Sassari Latte Dolce | 1:1 | ||
| 16:00 | Formia | - | Afragolese | 2:1 | ||
| 16:00 | Team Nuova Florida | - | Cassino Calcio 1924 | 2:2 | ||
| 16:00 | SEF Torres 1903 | - | Lanusei Calcio | 2:3 | ||
| 16:00 | ASD SS Nola 1925 | - | AC Savoia 1908 | 0:1 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Monterosi FC | 33 | 24 | 8 | 1 | 62:23 | 39 | 80 |
| 2 |
|
Latina Calcio | 33 | 18 | 8 | 7 | 57:27 | 30 | 62 |
| 3 |
|
AC Savoia 1908 | 33 | 13 | 15 | 5 | 37:21 | 16 | 54 |
| 4 |
|
ASD Vis Artena | 33 | 16 | 4 | 13 | 51:43 | 8 | 52 |
| 5 |
|
ASG Nocerina | 33 | 13 | 13 | 7 | 51:32 | 19 | 52 |
| 6 |
|
Formia | 33 | 13 | 11 | 9 | 50:36 | 14 | 50 |
| 7 |
|
Lanusei Calcio | 33 | 12 | 11 | 10 | 44:36 | 8 | 47 |
| 8 |
|
Muravera | 33 | 13 | 8 | 12 | 42:39 | 3 | 47 |
| 9 |
|
ASD Carbonia Calcio | 33 | 12 | 9 | 12 | 53:52 | 1 | 45 |
| 10 |
|
Sassari Latte Dolce | 33 | 10 | 11 | 12 | 40:38 | 2 | 41 |
| 11 |
|
Cassino Calcio 1924 | 33 | 9 | 14 | 10 | 41:45 | -4 | 41 |
| 12 |
|
Team Nuova Florida | 33 | 8 | 15 | 10 | 38:46 | -8 | 39 |
| 13 |
|
Gladiator | 33 | 8 | 13 | 12 | 34:44 | -10 | 37 |
| 14 |
|
Arzachena | 33 | 7 | 15 | 11 | 38:47 | -9 | 36 |
| 15 |
|
SEF Torres 1903 | 33 | 7 | 10 | 16 | 30:48 | -18 | 31 |
| 16 |
|
Afragolese | 33 | 8 | 7 | 18 | 37:59 | -22 | 31 |
| 17 |
|
ASD SS Nola 1925 | 33 | 6 | 13 | 14 | 33:56 | -23 | 30 |
| 18 |
|
Giugliano | 33 | 5 | 5 | 23 | 25:71 | -46 | 20 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
