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| 15.02.2016 | 20:00 | Sparta Rotterdam | - | Jong PSV | 1:0 (0:0) | |
| 20:00 | FC Volendam | - | Helmond Sport | 2:1 (1:0) | ||
| 20:00 | MVV | - | Almere City FC | 0:0 (0:0) | ||
| 20:00 | FC Eindhoven | - | FC Oss | 4:0 (1:0) | ||
| 20:00 | FC Den Bosch | - | Achilles'29 | 1:2 (0:1) | ||
| 20:00 | Fortuna Sittard | - | Telstar | 0:3 (0:1) | ||
| 20:00 | VVV-Venlo | - | FC Dordrecht | 3:0 (1:0) | ||
| 20:00 | Jong Ajax | - | Go Ahead Eagles | 2:2 (0:1) | ||
| 20:00 | FC Emmen | - | NAC Breda | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Rotterdam | 24 | 18 | 4 | 2 | 61:24 | 37 | 58 |
| 2 |
|
VVV-Venlo | 25 | 15 | 4 | 6 | 56:22 | 34 | 49 |
| 3 |
|
FC Eindhoven | 25 | 14 | 5 | 6 | 42:29 | 13 | 47 |
| 4 |
|
NAC Breda | 25 | 14 | 4 | 7 | 49:24 | 25 | 46 |
| 5 |
|
FC Volendam | 25 | 11 | 7 | 7 | 41:28 | 13 | 40 |
| 6 |
|
FC Emmen | 25 | 12 | 4 | 9 | 41:36 | 5 | 40 |
| 7 |
|
Go Ahead Eagles | 24 | 11 | 3 | 10 | 37:31 | 6 | 36 |
| 8 |
|
Telstar | 25 | 9 | 5 | 11 | 41:40 | 1 | 32 |
| 9 |
|
Helmond Sport | 25 | 8 | 7 | 10 | 38:39 | -1 | 31 |
| 10 |
|
Jong Ajax | 24 | 8 | 7 | 9 | 40:43 | -3 | 31 |
| 11 |
|
Achilles'29 | 25 | 8 | 7 | 10 | 29:37 | -8 | 31 |
| 12 |
|
Jong PSV | 24 | 8 | 7 | 9 | 34:46 | -12 | 31 |
| 13 |
|
MVV | 25 | 8 | 6 | 11 | 37:49 | -12 | 30 |
| 14 |
|
FC Dordrecht | 25 | 8 | 5 | 12 | 33:45 | -12 | 29 |
| 15 |
|
FC Den Bosch | 25 | 6 | 10 | 9 | 28:32 | -4 | 28 |
| 16 |
|
FC Oss | 24 | 6 | 7 | 11 | 30:45 | -15 | 25 |
| 17 |
|
Fortuna Sittard | 25 | 7 | 4 | 14 | 28:56 | -28 | 25 |
| 18 |
|
Almere City FC | 24 | 5 | 6 | 13 | 34:50 | -16 | 21 |
| 19 |
|
RKC Waalwijk | 24 | 4 | 6 | 14 | 24:47 | -23 | 18 |
| Aufstieg | |
| Playoffs | |
| Playoffs | |
| Playoffs |
