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| H | Impact de Montréal | - | Carolina RailHawks | 1:0 (1:0) | ||
| R | Carolina RailHawks | - | Impact de Montréal | 2:0 (0:0) | ||
| H: 15.10.2010 01:30 | R: 18.10.2010 00:00 | Sieger: Carolina RailHawks | ||||
| H | Puerto Rico Islanders | - | Vancouver Whitecaps | 0:0 (0:0) | ||
| R | Vancouver Whitecaps | - | Puerto Rico Islanders | 0:2 (0:0, 0:0) n.V. | ||
| H: 15.10.2010 02:05 | R: 18.10.2010 01:00 | Sieger: Puerto Rico Islanders | ||||
