Achtelfinale
26.10.2021 FC Floreşti FC Floreşti - FC Sîngerei FC Sîngerei -:-
26.10.2021 FC Sfîntul Gheorghe FC Sfîntul Gheorghe - Victoria Bardar Victoria Bardar -:-
26.10.2021 FC Milsami FC Milsami - FCM Ungheni FCM Ungheni -:-
26.10.2021 Speranța Drochia Speranța Drochia - FC Zimbru FC Zimbru -:-
26.10.2021 CS Petrocub CS Petrocub - Olimp Comrat Olimp Comrat -:-
26.10.2021 FC Sheriff FC Sheriff - FC Saxan FC Saxan -:-
26.10.2021 CSF Bălţi CSF Bălţi - FC Cahul 2005 FC Cahul 2005 -:-
26.10.2021 Sparta Selemet Sparta Selemet - Dinamo Auto Dinamo Auto -:-
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