Achtelfinale
21.09.2022 20:30 Rentistas Rentistas - Progreso Progreso 0:3
21.09.2022 20:30 Albion Albion - La Luz La Luz 2:3
22.09.2022 01:00 Rampla Juniors Rampla Juniors - Nacional Nacional 3:0
22.09.2022 01:30 Plaza Colonia Plaza Colonia - Cerro Largo Cerro Largo 1:0
27.09.2022 20:30 Liverpool Liverpool - Montevideo Wanderers Montevideo Wanderers 4:0
29.09.2022 01:30 Defensor Sporting Defensor Sporting - River Plate River Plate 2:0
29.09.2022 01:30 Peñarol Peñarol - Boston River Boston River 4:3 i.E.
29.09.2022 02:00 Cerrito Cerrito - Montevideo City Torque Montevideo City Torque 3:5 i.E.
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