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| 05.02.2022 | 15:00 | AS Roma | - | Genoa CFC | 0:0 (0:0) | |
| 18:00 | Inter | - | AC Milan | 1:2 (1:0) | ||
| 20:45 | ACF Fiorentina | - | Lazio Roma | 0:3 (0:0) | ||
| 06.02.2022 | 12:30 | Atalanta | - | Cagliari Calcio | 1:2 (0:0) | |
| 15:00 | Bologna FC | - | Empoli FC | 0:0 (0:0) | ||
| 15:00 | Venezia FC | - | SSC Napoli | 0:2 (0:0) | ||
| 15:00 | Sampdoria | - | Sassuolo Calcio | 4:0 (2:0) | ||
| 18:00 | Udinese Calcio | - | Torino FC | 2:0 (0:0) | ||
| 20:45 | Juventus | - | Hellas Verona | 2:0 (1:0) | ||
| 07.02.2022 | 20:45 | US Salernitana 1919 | - | Spezia Calcio | 2:2 (2:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Inter | 24 | 16 | 5 | 3 | 55:21 | 34 | 53 |
| 2 |
|
SSC Napoli | 24 | 16 | 4 | 4 | 45:16 | 29 | 52 |
| 3 |
|
AC Milan | 24 | 16 | 4 | 4 | 49:26 | 23 | 52 |
| 4 |
|
Juventus | 24 | 13 | 6 | 5 | 36:21 | 15 | 45 |
| 5 |
|
Atalanta | 24 | 12 | 8 | 4 | 49:32 | 17 | 44 |
| 6 |
|
Lazio Roma | 24 | 11 | 6 | 7 | 49:39 | 10 | 39 |
| 7 |
|
AS Roma | 24 | 12 | 3 | 9 | 40:30 | 10 | 39 |
| 8 |
|
ACF Fiorentina | 24 | 11 | 3 | 10 | 41:37 | 4 | 36 |
| 9 |
|
Torino FC | 24 | 9 | 6 | 9 | 34:27 | 7 | 33 |
| 10 |
|
Hellas Verona | 24 | 9 | 6 | 9 | 43:40 | 3 | 33 |
| 11 |
|
Bologna FC | 24 | 9 | 4 | 11 | 31:38 | -7 | 31 |
| 12 |
|
Empoli FC | 24 | 8 | 6 | 10 | 37:47 | -10 | 30 |
| 13 |
|
Sassuolo Calcio | 24 | 7 | 8 | 9 | 39:42 | -3 | 29 |
| 14 |
|
Udinese Calcio | 24 | 6 | 9 | 9 | 34:37 | -3 | 27 |
| 15 |
|
Spezia Calcio | 24 | 7 | 5 | 12 | 26:44 | -18 | 26 |
| 16 |
|
Sampdoria | 24 | 6 | 5 | 13 | 33:41 | -8 | 23 |
| 17 |
|
Cagliari Calcio | 24 | 4 | 8 | 12 | 24:45 | -21 | 20 |
| 18 |
|
Venezia FC | 24 | 4 | 6 | 14 | 21:44 | -23 | 18 |
| 19 |
|
US Salernitana 1919 | 24 | 5 | 3 | 16 | 19:53 | -34 | 18 |
| 20 |
|
Genoa CFC | 24 | 1 | 11 | 12 | 20:45 | -25 | 14 |
| Champions League | |
| Europa League | |
| Europa Conference League Quali. | |
| Abstieg |
