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| H | Albinegros Orizaba | - | Club Tijuana | 0:0 (0:0) | ||
| R | Club Tijuana | - | Albinegros Orizaba | 0:0 (0:0) | ||
| H: 26.11.2010 02:00 | R: 28.11.2010 22:00 | |||||
| H | Club Irapuato | - | Veracruz (old) | 2:0 (1:0) | ||
| R | Veracruz (old) | - | Club Irapuato | 3:1 (1:0) | ||
| H: 26.11.2010 03:50 | R: 29.11.2010 02:00 | Sieger: Club Irapuato | ||||
