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| 05.05.2018 | 16:00 | Gallos Blancos | - | Atlas Guadalajara | 0:1 | |
| 16:30 | Monarcas Morelia | - | Santos Laguna | 1:3 | ||
| 17:00 | Pumas UNAM | - | CF Pachuca | 1:0 | ||
| 17:00 | Lobos BUAP | - | Deportivo Toluca | 2:3 | ||
| 19:00 | Puebla FC | - | Cruz Azul | 1:2 | ||
| 23:00 | CF América | - | Club Tijuana | 3:2 | ||
| 23:00 | Deportivo Guadalajara | - | Club Necaxa | 4:0 | ||
| 23:00 | CF Monterrey | - | UANL Tigres | 2:0 |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF América | 16 | 10 | 3 | 3 | 24:12 | 12 | 33 |
| 2 |
|
CF Pachuca | 16 | 10 | 2 | 4 | 34:14 | 20 | 32 |
| 3 |
|
Pumas UNAM | 16 | 9 | 4 | 3 | 23:10 | 13 | 31 |
| 4 |
|
Deportivo Toluca | 16 | 9 | 1 | 6 | 21:19 | 2 | 28 |
| 5 |
|
Club Tijuana | 16 | 7 | 4 | 5 | 20:11 | 9 | 25 |
| 6 |
|
CD Veracruz | 16 | 6 | 5 | 5 | 22:24 | -2 | 23 |
| 7 |
|
Cruz Azul | 16 | 5 | 4 | 7 | 12:16 | -4 | 19 |
| 8 |
|
Puebla FC | 16 | 3 | 2 | 11 | 11:35 | -24 | 11 |
| 9 |
|
Lobos BUAP | 16 | 0 | 1 | 15 | 9:35 | -26 | 1 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlas Guadalajara | 16 | 12 | 1 | 3 | 35:18 | 17 | 37 |
| 2 |
|
Deportivo Guadalajara | 16 | 10 | 2 | 4 | 34:18 | 16 | 32 |
| 3 |
|
Monarcas Morelia | 16 | 8 | 3 | 5 | 35:25 | 10 | 27 |
| 4 |
|
CF Monterrey | 16 | 7 | 5 | 4 | 25:22 | 3 | 26 |
| 5 |
|
Santos Laguna | 16 | 5 | 4 | 7 | 20:25 | -5 | 19 |
| 6 |
|
UANL Tigres | 16 | 5 | 4 | 7 | 17:22 | -5 | 19 |
| 7 |
|
Gallos Blancos | 16 | 5 | 3 | 8 | 20:22 | -2 | 18 |
| 8 |
|
Club León | 16 | 3 | 4 | 9 | 19:34 | -15 | 13 |
| 9 |
|
Club Necaxa | 16 | 2 | 4 | 10 | 18:37 | -19 | 10 |
