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| 18.01.2008 | 20:00 | BV Veendam | - | FC Zwolle | 2:2 (0:2) | |
| 20:00 | Stormvogels Telstar | - | TOP Oss | 1:1 (0:0) | ||
| 20:00 | MVV | - | RKC Waalwijk | 1:1 (0:0) | ||
| 20:00 | FC Eindhoven | - | HFC Haarlem | 2:2 (0:2) | ||
| 20:00 | Go Ahead Eagles | - | FC Volendam | 1:2 (0:1) | ||
| 20:00 | AGOVV | - | Fortuna Sittard | 2:3 (2:2) | ||
| 20:00 | ADO Den Haag | - | FC Dordrecht | 2:1 (2:0) | ||
| 20:00 | RBC Roosendaal | - | SC Cambuur | 1:0 (0:0) | ||
| 20:00 | FC Omniworld | - | FC Emmen | 4:1 (1:0) | ||
| 20.01.2008 | 14:30 | FC Den Bosch | - | Helmond Sport | 0:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 24 | 13 | 9 | 2 | 56:31 | 25 | 48 |
| 2 |
|
FC Zwolle | 24 | 12 | 8 | 4 | 46:28 | 18 | 44 |
| 3 |
|
FC Volendam | 24 | 11 | 9 | 4 | 56:32 | 24 | 42 |
| 4 |
|
MVV | 24 | 12 | 6 | 6 | 40:29 | 11 | 42 |
| 5 |
|
FC Den Bosch | 24 | 13 | 3 | 8 | 39:31 | 8 | 42 |
| 6 |
|
Go Ahead Eagles | 24 | 13 | 0 | 11 | 42:42 | 0 | 39 |
| 7 |
|
ADO Den Haag | 24 | 10 | 6 | 8 | 38:36 | 2 | 36 |
| 8 |
|
RBC Roosendaal | 24 | 9 | 8 | 7 | 33:27 | 6 | 35 |
| 9 |
|
Helmond Sport | 24 | 10 | 5 | 9 | 30:32 | -2 | 35 |
| 10 |
|
TOP Oss | 24 | 8 | 8 | 8 | 37:42 | -5 | 32 |
| 11 |
|
FC Dordrecht | 24 | 8 | 7 | 9 | 45:33 | 12 | 31 |
| 12 |
|
FC Emmen | 24 | 7 | 8 | 9 | 35:46 | -11 | 29 |
| 13 |
|
BV Veendam | 24 | 7 | 10 | 7 | 38:40 | -2 | 28 |
| 14 |
|
Stormvogels Telstar | 24 | 8 | 3 | 13 | 24:32 | -8 | 27 |
| 15 |
|
FC Omniworld | 24 | 5 | 9 | 10 | 38:35 | 3 | 24 |
| 16 |
|
HFC Haarlem | 24 | 5 | 9 | 10 | 29:36 | -7 | 24 |
| 17 |
|
AGOVV | 24 | 8 | 3 | 13 | 36:59 | -23 | 24 |
| 18 |
|
Fortuna Sittard | 24 | 6 | 5 | 13 | 26:40 | -14 | 23 |
| 19 |
|
SC Cambuur | 24 | 6 | 5 | 13 | 29:45 | -16 | 23 |
| 20 |
|
FC Eindhoven | 24 | 6 | 5 | 13 | 33:54 | -21 | 23 |
| Aufstieg |
|
# 3 Punkte Abzug für AGOVV und BV Veendam. |
