 |
 |
|
|
| 05.11.2021 | 17:00 | AS Trenčín | - | MFK Zemplín Michalovce | 4:2 (2:0) | |
| 06.11.2021 | 15:00 | FK Senica | - | Zlaté Moravce | 1:2 (1:1) | |
| 15:00 | FK Pohronie | - | MŠK Žilina | 1:2 (1:2) | ||
| 15:00 | FC DAC 1904 | - | ŠKF Sereď | 1:3 (1:1) | ||
| 07.11.2021 | 15:00 | Slovan Bratislava | - | MFK Ružomberok | 1:0 (1:0) | |
| 17:00 | Tatran Liptovský Mikuláš | - | Spartak Trnava | 0:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 14 | 11 | 2 | 1 | 36:10 | 26 | 35 |
| 2 |
|
Spartak Trnava | 14 | 10 | 2 | 2 | 24:8 | 16 | 32 |
| 3 |
|
MFK Ružomberok | 14 | 6 | 6 | 2 | 21:12 | 9 | 24 |
| 4 |
|
MŠK Žilina | 14 | 6 | 3 | 5 | 22:17 | 5 | 21 |
| 5 |
|
FC DAC 1904 | 14 | 6 | 3 | 5 | 20:19 | 1 | 21 |
| 6 |
|
AS Trenčín | 14 | 5 | 5 | 4 | 24:19 | 5 | 20 |
| 7 |
|
MFK Zemplín Michalovce | 14 | 5 | 2 | 7 | 16:20 | -4 | 17 |
| 8 |
|
ŠKF Sereď | 14 | 4 | 4 | 6 | 15:19 | -4 | 16 |
| 9 |
|
FK Senica | 14 | 3 | 5 | 6 | 14:22 | -8 | 14 |
| 10 |
|
Tatran Liptovský Mikuláš | 14 | 4 | 1 | 9 | 17:32 | -15 | 13 |
| 11 |
|
Zlaté Moravce | 14 | 2 | 4 | 8 | 15:30 | -15 | 10 |
| 12 |
|
FK Pohronie | 14 | 2 | 3 | 9 | 13:29 | -16 | 9 |
| Playoffs | |
| Relegation |
