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| 20.04.2000 | VfB Marburg | - | VfB Gießen | 0:0 | ||
| SG 01 Hoechst | - | FV Bad Vilbel | 1:1 | |||
| 22.04.2000 | KSV Klein-Karben | - | FC Ederbergland | 4:1 | ||
| Viktoria Aschaffenburg | - | SC Neukirchen | 6:1 | |||
| Eintracht Frankfurt II | - | TGM SV Jügesheim | 0:0 | |||
| FSC Lohfelden | - | SV Bernbach | 1:1 | |||
| SGV Germania Horbach | - | VfB Unterliederbach | 3:1 | |||
| SVA Bad Hersfeld | - | Kickers Offenbach II | 1:4 | |||
| FSV Braunfels | - | KSV Baunatal | 3:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Neukirchen | 28 | 15 | 6 | 7 | 61:42 | 19 | 51 |
| 2 |
|
KSV Klein-Karben | 28 | 13 | 10 | 5 | 50:30 | 20 | 49 |
| 3 |
|
FV Bad Vilbel | 28 | 12 | 12 | 4 | 47:27 | 20 | 48 |
| 4 |
|
FSC Lohfelden | 28 | 14 | 5 | 9 | 68:55 | 13 | 47 |
| 5 |
|
Eintracht Frankfurt II | 28 | 12 | 8 | 8 | 45:32 | 13 | 44 |
| 6 |
|
Viktoria Aschaffenburg | 28 | 10 | 11 | 7 | 47:33 | 14 | 41 |
| 7 |
|
SG 01 Hoechst | 28 | 11 | 8 | 9 | 54:47 | 7 | 41 |
| 8 |
|
SV Bernbach | 28 | 12 | 5 | 11 | 55:49 | 6 | 41 |
| 9 |
|
SGV Germania Horbach | 28 | 10 | 9 | 9 | 43:45 | -2 | 39 |
| 10 |
|
TGM SV Jügesheim | 28 | 11 | 6 | 11 | 43:48 | -5 | 39 |
| 11 |
|
FC Ederbergland | 28 | 10 | 8 | 10 | 45:40 | 5 | 38 |
| 12 |
|
VfB Gießen | 28 | 8 | 11 | 9 | 49:50 | -1 | 35 |
| 13 |
|
VfB Marburg | 28 | 8 | 10 | 10 | 41:51 | -10 | 34 |
| 14 |
|
SVA Bad Hersfeld | 28 | 9 | 6 | 13 | 44:55 | -11 | 33 |
| 15 |
|
Kickers Offenbach II | 28 | 9 | 6 | 13 | 52:66 | -14 | 33 |
| 16 |
|
KSV Baunatal | 28 | 8 | 7 | 13 | 40:52 | -12 | 31 |
| 17 |
|
FSV Braunfels | 28 | 5 | 7 | 16 | 33:63 | -30 | 22 |
| 18 |
|
VfB Unterliederbach | 28 | 5 | 5 | 18 | 38:70 | -32 | 20 |
