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| 27.11.2021 | 16:00 | SC Velbert | - | Sportfreunde Baumberg | 0:3 (0:0) | |
| 28.11.2021 | 15:00 | Sportfreunde Niederwenigern | - | SC Düsseldorf-West | 0:2 (0:0) | |
| 15:00 | 1. FC Monheim | - | SSVg Velbert | 0:3 (0:1) | ||
| 15:00 | SpVg Schonnebeck | - | Cronenberger SC | 3:1 (0:0) | ||
| 15:00 | TV Jahn Hiesfeld | - | SC Union Nettetal | 1:3 (0:1) | ||
| 15:00 | Germania Ratingen 04/19 | - | TVD Velbert | 1:2 (0:1) | ||
| 15:30 | TuRU Düsseldorf | - | SpVgg Sterkrade-Nord | 1:1 (0:1) | ||
| 15:30 | DJK Teutonia St. Tönis | - | Schwarz-Weiß Essen | 0:3 (0:2) | ||
| 15:30 | FSV Duisburg | - | TSV Meerbusch | 1:1 (0:0) | ||
| 15:30 | VfB 03 Hilden | - | 1. FC Kleve | 4:0 (3:0) | ||
| 15:30 | 1. FC Mönchengladbach | - | 1. FC Bocholt | 2:4 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSVg Velbert | 13 | 11 | 2 | 0 | 40:10 | 30 | 35 |
| 2 |
|
VfB 03 Hilden | 13 | 11 | 1 | 1 | 35:11 | 24 | 34 |
| 3 |
|
1. FC Bocholt | 13 | 9 | 3 | 1 | 46:13 | 33 | 30 |
| 4 |
|
SpVg Schonnebeck | 13 | 7 | 4 | 2 | 32:17 | 15 | 25 |
| 5 |
|
1. FC Kleve | 14 | 7 | 4 | 3 | 22:18 | 4 | 25 |
| 6 |
|
Germania Ratingen 04/19 | 14 | 7 | 2 | 5 | 34:25 | 9 | 23 |
| 7 |
|
1. FC Monheim | 14 | 7 | 2 | 5 | 24:20 | 4 | 23 |
| 8 |
|
TVD Velbert | 13 | 7 | 1 | 5 | 22:21 | 1 | 22 |
| 9 |
|
TSV Meerbusch | 13 | 7 | 1 | 5 | 27:25 | 2 | 22 |
| 10 |
|
Sportfreunde Baumberg | 14 | 7 | 0 | 7 | 26:23 | 3 | 21 |
| 11 |
|
SC Union Nettetal | 14 | 6 | 1 | 7 | 22:23 | -1 | 19 |
| 12 |
|
Schwarz-Weiß Essen | 13 | 6 | 1 | 6 | 22:26 | -4 | 19 |
| 13 |
|
TuRU Düsseldorf | 14 | 5 | 3 | 6 | 21:26 | -5 | 18 |
| 14 |
|
FC Kray | 13 | 4 | 3 | 6 | 19:30 | -11 | 15 |
| 15 |
|
Sportfreunde Niederwenigern | 13 | 3 | 5 | 5 | 18:28 | -10 | 14 |
| 16 |
|
DJK Teutonia St. Tönis | 14 | 4 | 2 | 8 | 19:30 | -11 | 14 |
| 17 |
|
SC Düsseldorf-West | 14 | 4 | 2 | 8 | 18:29 | -11 | 14 |
| 18 |
|
SC Velbert | 13 | 3 | 4 | 6 | 19:21 | -2 | 13 |
| 19 |
|
Cronenberger SC | 14 | 3 | 4 | 7 | 16:32 | -16 | 13 |
| 20 |
|
TV Jahn Hiesfeld | 13 | 3 | 2 | 8 | 16:23 | -7 | 11 |
| 21 |
|
FSV Duisburg | 13 | 2 | 4 | 7 | 14:19 | -5 | 10 |
| 22 |
|
1. FC Mönchengladbach | 13 | 3 | 1 | 9 | 18:39 | -21 | 10 |
| 23 |
|
SpVgg Sterkrade-Nord | 13 | 1 | 2 | 10 | 16:37 | -21 | 5 |
| Playoffs | |
| Playoffs |
