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| 17.03.2023 | 19:30 | TuS Bövinghausen | - | Preußen Münster II | 2:2 (0:1) | |
| 19:30 | TSG Sprockhövel | - | SC Paderborn 07 II | 2:2 (0:0) | ||
| 19.03.2023 | 15:00 | SV Schermbeck | - | SG Finnentrop/Bamenohl | 1:1 (1:1) | |
| 15:00 | Viktoria Clarholz | - | Sportfreunde Lotte | 1:2 (0:1) | ||
| 15:00 | Delbrücker SC | - | TuS Ennepetal | 1:1 (1:1) | ||
| 15:00 | ASC 09 Dortmund | - | FC Gütersloh | 1:4 (0:2) | ||
| 15:00 | Sportfreunde Siegen | - | 1. FC Gievenbeck | 1:1 (1:1) | ||
| 15:00 | SpVgg Vreden | - | Westfalia Rhynern | 4:0 (2:0) | ||
| 16:00 | TuS Erndtebrück | - | FCE Rheine | 3:1 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster II | 23 | 14 | 7 | 2 | 56:27 | 29 | 49 |
| 2 |
|
TuS Bövinghausen | 23 | 14 | 4 | 5 | 51:32 | 19 | 46 |
| 3 |
|
FC Gütersloh | 23 | 14 | 3 | 6 | 48:31 | 17 | 45 |
| 4 |
|
SC Paderborn 07 II | 23 | 11 | 7 | 5 | 34:18 | 16 | 40 |
| 5 |
|
Westfalia Rhynern | 23 | 11 | 7 | 5 | 35:26 | 9 | 40 |
| 6 |
|
Sportfreunde Lotte | 23 | 10 | 5 | 8 | 40:32 | 8 | 35 |
| 7 |
|
SG Finnentrop/Bamenohl | 23 | 10 | 4 | 9 | 47:39 | 8 | 34 |
| 8 |
|
SV Schermbeck | 23 | 9 | 6 | 8 | 32:31 | 1 | 33 |
| 9 |
|
FCE Rheine | 23 | 10 | 3 | 10 | 34:36 | -2 | 33 |
| 10 |
|
ASC 09 Dortmund | 23 | 10 | 3 | 10 | 31:36 | -5 | 33 |
| 11 |
|
Viktoria Clarholz | 23 | 9 | 4 | 10 | 35:36 | -1 | 31 |
| 12 |
|
SpVgg Vreden | 23 | 8 | 5 | 10 | 38:42 | -4 | 29 |
| 13 |
|
TuS Erndtebrück | 23 | 7 | 5 | 11 | 35:58 | -23 | 26 |
| 14 |
|
TuS Ennepetal | 23 | 6 | 5 | 12 | 21:38 | -17 | 23 |
| 15 |
|
1. FC Gievenbeck | 23 | 5 | 7 | 11 | 30:39 | -9 | 22 |
| 16 |
|
TSG Sprockhövel | 23 | 5 | 6 | 12 | 32:49 | -17 | 21 |
| 17 |
|
Sportfreunde Siegen | 23 | 4 | 7 | 12 | 30:37 | -7 | 19 |
| 18 |
|
Delbrücker SC | 23 | 3 | 6 | 14 | 26:48 | -22 | 15 |
| Aufstieg | |
| Aufstieg | |
| Abstieg |
