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| 06.04.2023 | 17:30 | 1. FC Gievenbeck | - | Preußen Münster II | 1:1 (1:1) | |
| 19:00 | TuS Ennepetal | - | SpVgg Vreden | 1:1 (0:0) | ||
| 19:00 | FC Gütersloh | - | SG Finnentrop/Bamenohl | 1:0 (1:0) | ||
| 19:00 | Sportfreunde Lotte | - | Sportfreunde Siegen | 2:0 (0:0) | ||
| 19:00 | Westfalia Rhynern | - | SV Schermbeck | 1:1 (0:1) | ||
| 19:00 | TSG Sprockhövel | - | Viktoria Clarholz | 0:0 (0:0) | ||
| 19:00 | Delbrücker SC | - | TuS Bövinghausen | 1:1 (1:0) | ||
| 19:00 | SC Paderborn 07 II | - | TuS Erndtebrück | 2:0 (1:0) | ||
| 19:30 | FCE Rheine | - | ASC 09 Dortmund | 2:2 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Gütersloh | 26 | 17 | 3 | 6 | 55:33 | 22 | 54 |
| 2 |
|
Preußen Münster II | 26 | 15 | 8 | 3 | 60:31 | 29 | 53 |
| 3 |
|
TuS Bövinghausen | 26 | 14 | 6 | 6 | 55:40 | 15 | 48 |
| 4 |
|
SC Paderborn 07 II | 26 | 13 | 8 | 5 | 39:18 | 21 | 47 |
| 5 |
|
Sportfreunde Lotte | 26 | 12 | 6 | 8 | 46:33 | 13 | 42 |
| 6 |
|
Westfalia Rhynern | 26 | 11 | 9 | 6 | 38:30 | 8 | 42 |
| 7 |
|
SG Finnentrop/Bamenohl | 26 | 11 | 4 | 11 | 55:45 | 10 | 37 |
| 8 |
|
ASC 09 Dortmund | 26 | 10 | 6 | 10 | 37:42 | -5 | 36 |
| 9 |
|
FCE Rheine | 26 | 10 | 5 | 11 | 40:44 | -4 | 35 |
| 10 |
|
Viktoria Clarholz | 26 | 9 | 7 | 10 | 37:38 | -1 | 34 |
| 11 |
|
SV Schermbeck | 26 | 9 | 7 | 10 | 34:40 | -6 | 34 |
| 12 |
|
SpVgg Vreden | 26 | 8 | 8 | 10 | 42:46 | -4 | 32 |
| 13 |
|
TuS Ennepetal | 26 | 7 | 7 | 12 | 25:41 | -16 | 28 |
| 14 |
|
1. FC Gievenbeck | 26 | 6 | 9 | 11 | 37:42 | -5 | 27 |
| 15 |
|
TuS Erndtebrück | 26 | 7 | 5 | 14 | 35:64 | -29 | 26 |
| 16 |
|
Sportfreunde Siegen | 26 | 6 | 7 | 13 | 35:41 | -6 | 25 |
| 17 |
|
TSG Sprockhövel | 26 | 5 | 8 | 13 | 32:52 | -20 | 23 |
| 18 |
|
Delbrücker SC | 26 | 4 | 7 | 15 | 30:52 | -22 | 19 |
| Aufstieg | |
| Aufstieg | |
| Abstieg |
