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| 15.04.2023 | 14:00 | SC Paderborn 07 II | - | Sportfreunde Siegen | 0:0 (0:0) | |
| 16.04.2023 | 15:00 | Delbrücker SC | - | TuS Erndtebrück | 3:2 (1:1) | |
| 15:00 | FCE Rheine | - | Preußen Münster II | 1:0 (1:0) | ||
| 15:00 | 1. FC Gievenbeck | - | FC Gütersloh | 0:1 (0:0) | ||
| 15:00 | TSG Sprockhövel | - | SpVgg Vreden | 1:1 (0:1) | ||
| 15:00 | Sportfreunde Lotte | - | SV Schermbeck | 1:0 (1:0) | ||
| 15:00 | Viktoria Clarholz | - | TuS Bövinghausen | 1:1 (1:0) | ||
| 15:00 | Westfalia Rhynern | - | SG Finnentrop/Bamenohl | 1:1 (0:1) | ||
| 15:30 | TuS Ennepetal | - | ASC 09 Dortmund | 1:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Gütersloh | 28 | 19 | 3 | 6 | 58:34 | 24 | 60 |
| 2 |
|
Preußen Münster II | 28 | 16 | 8 | 4 | 64:33 | 31 | 56 |
| 3 |
|
TuS Bövinghausen | 28 | 14 | 7 | 7 | 57:43 | 14 | 49 |
| 4 |
|
SC Paderborn 07 II | 28 | 13 | 9 | 6 | 41:21 | 20 | 48 |
| 5 |
|
Sportfreunde Lotte | 28 | 14 | 6 | 8 | 49:33 | 16 | 48 |
| 6 |
|
Westfalia Rhynern | 28 | 11 | 10 | 7 | 40:35 | 5 | 43 |
| 7 |
|
SG Finnentrop/Bamenohl | 28 | 12 | 5 | 11 | 58:46 | 12 | 41 |
| 8 |
|
FCE Rheine | 28 | 11 | 6 | 11 | 43:46 | -3 | 39 |
| 9 |
|
ASC 09 Dortmund | 28 | 11 | 6 | 11 | 39:45 | -6 | 39 |
| 10 |
|
SpVgg Vreden | 28 | 9 | 9 | 10 | 46:49 | -3 | 36 |
| 11 |
|
Viktoria Clarholz | 28 | 9 | 8 | 11 | 39:42 | -3 | 35 |
| 12 |
|
SV Schermbeck | 28 | 9 | 8 | 11 | 36:43 | -7 | 35 |
| 13 |
|
TuS Ennepetal | 28 | 8 | 7 | 13 | 27:43 | -16 | 31 |
| 14 |
|
1. FC Gievenbeck | 28 | 6 | 9 | 13 | 37:45 | -8 | 27 |
| 15 |
|
TSG Sprockhövel | 28 | 6 | 9 | 13 | 37:55 | -18 | 27 |
| 16 |
|
Sportfreunde Siegen | 28 | 6 | 8 | 14 | 35:42 | -7 | 26 |
| 17 |
|
TuS Erndtebrück | 28 | 7 | 5 | 16 | 39:71 | -32 | 26 |
| 18 |
|
Delbrücker SC | 28 | 6 | 7 | 15 | 36:55 | -19 | 25 |
| Aufstieg | |
| Aufstieg | |
| Abstieg |
