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| 17.03.2006 | 19:00 | Eintracht Trier | - | 1. FC Eschborn | 1:0 (1:0) | |
| 18.03.2006 | 14:30 | Stuttgarter Kickers | - | SV Darmstadt 98 | 1:1 (0:1) | |
| 14:30 | SV Wehen-Taunusstein | - | FC Augsburg | 3:1 (1:0) | ||
| 14:30 | Karlsruher SC II | - | VfB Stuttgart II | 3:2 (2:1) | ||
| 14:30 | Jahn Regensburg | - | SpVgg Bayreuth | 0:1 (0:0) | ||
| 19.03.2006 | 15:00 | 1. FC Kaiserslautern II | - | TSV 1860 München II | 1:0 (1:0) | |
| 28.03.2006 | 19:00 | SC Pfullendorf | - | SV 07 Elversberg | 3:1 (1:1) | |
| 05.04.2006 | 19:00 | VfR Aalen | - | TuS Koblenz | 1:1 (0:0) | |
| 25.04.2006 | 18:00 | Bayern München II | - | TSG Hoffenheim | 2:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Augsburg | 24 | 16 | 5 | 3 | 51:19 | 32 | 53 |
| 2 |
|
TuS Koblenz | 24 | 11 | 9 | 4 | 36:24 | 12 | 42 |
| 3 |
|
TSG Hoffenheim | 24 | 13 | 3 | 8 | 34:22 | 12 | 42 |
| 4 |
|
SV Wehen-Taunusstein | 24 | 11 | 4 | 9 | 45:36 | 9 | 37 |
| 5 |
|
SV Darmstadt 98 | 24 | 11 | 4 | 9 | 37:31 | 6 | 37 |
| 6 |
|
Stuttgarter Kickers | 24 | 10 | 7 | 7 | 35:29 | 6 | 37 |
| 7 |
|
VfB Stuttgart II | 24 | 10 | 7 | 7 | 41:37 | 4 | 37 |
| 8 |
|
Karlsruher SC II | 24 | 11 | 4 | 9 | 33:31 | 2 | 37 |
| 9 |
|
VfR Aalen | 24 | 10 | 6 | 8 | 29:25 | 4 | 36 |
| 10 |
|
SpVgg Bayreuth | 24 | 8 | 10 | 6 | 36:33 | 3 | 34 |
| 11 |
|
SV 07 Elversberg | 24 | 8 | 9 | 7 | 27:26 | 1 | 33 |
| 12 |
|
Bayern München II | 24 | 8 | 7 | 9 | 23:30 | -7 | 31 |
| 13 |
|
1. FC Kaiserslautern II | 24 | 8 | 4 | 12 | 26:29 | -3 | 28 |
| 14 |
|
Jahn Regensburg | 24 | 6 | 8 | 10 | 32:35 | -3 | 26 |
| 15 |
|
TSV 1860 München II | 24 | 6 | 8 | 10 | 29:40 | -11 | 26 |
| 16 |
|
SC Pfullendorf | 24 | 6 | 6 | 12 | 17:27 | -10 | 24 |
| 17 |
|
Eintracht Trier | 24 | 6 | 5 | 13 | 30:47 | -17 | 23 |
| 18 |
|
1. FC Eschborn | 24 | 1 | 6 | 17 | 12:52 | -40 | 9 |
