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| H | FC Steaua Bucureşti | - | Middlesbrough FC | 1:0 (1:0) | ||
| R | Middlesbrough FC | - | FC Steaua Bucureşti | 4:2 (1:2) | ||
| H: 20.04.2006 19:45 | R: 27.04.2006 21:00 | Sieger: Middlesbrough FC | ||||
| H | FC Schalke 04 | - | Sevilla FC | 0:0 (0:0) | ||
| R | Sevilla FC | - | FC Schalke 04 | 1:0 (0:0, 0:0) n.V. | ||
| H: 20.04.2006 20:30 | R: 27.04.2006 21:30 | Sieger: Sevilla FC | ||||
